\"Nobel Prize in Chemistry\" Martin Chalfie Signed 3X4 Color Photo For Sale

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\"Nobel Prize in Chemistry\" Martin Chalfie Signed 3X4 Color Photo:
$99.99

Up for sale the "Nobel Prize in Chemistry" Martin Chalfie Signed 3X4 Color Photo. 



ES-5765E

Martin

Lee Chalfie (born January 15,

1947) is an American scientist. He is University Professor at Columbia University. He

shared the 2008 Nobel Prize in Chemistry along

with Osamu Shimomura and Roger Y. Tsien "for the discovery and development of

the green fluorescent protein,

GFP". He holds University. Chalfie

grew up in Chicago, Illinois, son of

the guitarist Eli Chalfie (1910—1996) and owner of an apparel store Vivian

Chalfie (née Friedlen, 1913—2005). His maternal grandfather, Meyer L. Friedlen,

immigrated to Chicago from Moscow at an early age; his paternal

grandparents, Benjamin and Esther Chalfie, came to Cincinnati from Brest-Litovsk. He

matriculated at Harvard University in

1965, intending to be a math major, but he switched to biochemistry

because it combined his interests in chemistry, math, and biology. He spent the

summer after his junior year working in the laboratory of Klaus Weber at Harvard, but "It was so disheartening

to completely fail that I decided I shouldn't be in biology. As a result, in his senior year, he completed

his major and took courses in law, theater, and Russian literature. He

also competed on the swim team at Harvard and was named captain in his senior

year. At the time, swimming coach Bill Brooks said, "Marty will make an

excellent captain because he has the admiration of the entire team." As

captain, he won the Harold S. Ulen trophy, awarded "to a senior on the

Harvard team who best demonstrates those qualities of leadership,

sportsmanship, and team cooperation as exemplified by Harold S. Ulen."  Following

the announcement of Chalfie's Nobel award, his freshman-year roommate observed

of Chalfie, "He would always identify himself as a swimmer."

After graduating in 1969, he worked at a variety of temporary jobs, such

as selling dresses for his parents' dress manufacturing business in

Chicago  and teaching at Hamden Hall Country Day

School in Hamden, Connecticut. In the summer of 1971, his research at the

laboratory of Jose

Zadunaisky at Yale University resulted in his first publication. With

revived confidence, he returned to Harvard for graduate and received his Ph.D. in

1977. Chalfie conducted his postdoctoral research at the Laboratory of Molecular

Biology (LMB) with Sydney Brenner and John Sulston,

and the three published a paper in 1985 on "The Neural Circuit for Touch

Sensitivity in C. elegans". Chalfie then left the LMB in 1982 to join the

faculty of Columbia University in

the department of biological sciences and continued to study C. elegans touch

mutants. He married Tulle

Hazelrigg. She later joined him on the faculty of Columbia University. She

gave him permission to cite her unpublished research in his seminal Science

paper "Green Fluorescent Protein as a Marker for Gene Expression" on

condition that he made coffee, cooked, and emptied the garbage nightly for a

month. Chalfie and his wife had a daughter, Sarah, in July 1992. He

slept through the phone call from the Nobel Prize Committee. When he woke

up, he knew the prize would have been announced already, so he said "Okay,

who's the schnook that got the Prize this time?" And so he

opened up his laptop, got to the Nobel Prize site and found out that he was the

schnook! In 2015, Chalfie signed the Mainau Declaration 2015 on Climate

Change on the final day of the 65th Lindau Nobel Laureate

Meeting. The declaration was signed by a total of 76 Nobel Laureates

and handed to then-President of the French Republic, François Hollande, as part

of the successful COP21 climate summit in

Paris.v Chalfie's lab uses the nematode C. elegans to

investigate aspects of nerve cell development and function. The wealth of

developmental, anatomical, genetic, and molecular information available

for C. elegans provides a powerful and multifaceted approach

to these studies. He has published over 100 papers of which at least 25 have

over 100 citations. He traces his work on green fluorescent protein to

a 1988 seminar from Paul Brehm about

bioluminescent organisms, which led to some crucial experiments in 1992,

detailed in his paper "Green fluorescent protein as a marker for gene

expression", which is among the 20 most-cited papers in the field of

Molecular Biology & Genetics. Chalfie won a Golden Goose Award for

this work in 2012. 



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