"Nobel Prize In Medicine" Bernard Katz Hand Written Letter COA For Sale

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"Nobel Prize In Medicine" Bernard Katz Hand Written Letter COA:
$279.99

SirBernard Katz,FRS(26 March 1911 – 20 April 2003)was a German-bornBritishphysician andbiophysicist, noted for his work onnervephysiology. He shared the Nobel Prize inphysiologyor medicinein 1970 withJulius AxelrodandUlf von Euler. He was made aKnight Bachelorin 1969. Katz was born inLeipzig, Germany, to a Jewish family originally from Russia,the son of Eugenie (Rabinowitz) and Max Katz, a fur merchant. He was educated at the Albert Gymnasium in thatcity from 1921 to 1929 and went on to study medicine at theUniversity of Leipzig. Hegraduated in 1934 and fled to Britain in February 1935 Katz went to workatUniversity College London,initially under the tutelage ofArchibald Vivian Hill. Hefinished his PhD in 1938 and won aCarnegie Fellowshiptostudy withJohn Carew Ecclesatthe Kanematsu Institute ofSydney Medical School.During this time, both he and Eccles gaveresearch lectures at theUniversity of Sydney.He obtained British nationality in 1941and joined theRoyal Australian Air Forcein1942. He spent the war in the Pacific as aradarofficerand returned to UCL as an assistant director in 1946. Back in England he alsoworked with the 1963 Nobel prize winnersAlan HodgkinandAndrew Huxley. Katz was made a professor at UCL in 1952 andhead of biophysics, he was elected aFellow of the Royal Society (FRS) in 1952.He stayed as head of biophysics until 1978 whenhe became emeritus professor. Katz married Marguerite Penly in 1945. He died inLondon on 20 April 2003, at the age of 92. He is survived by his two sons,David and Jonathan.David is a practising doctor, while JonathanisPublic OratorofTheUniversity of Oxford. Hisresearch uncovered fundamental properties ofsynapses, the junctions across which nerve cells signal toeach other and to other types of cells. By the 1950s, he was studying thebiochemistry and action ofacetylcholine, asignalling moleculefound in synapses linkingmotor neuronstomuscles,used to stimulate contraction. Katz won theNobel for his discovery withPaul Fattthat neurotransmitter release at synapses is"quantal",meaning that at any particular synapse, the amount of neurotransmitter releasedis never less than a certain amount, and if more is always an integral numbertimes this amount. Scientists now understand that this circumstance arisesbecause, prior to their release into the synaptic gap, transmitter moleculesreside in like-sized subcellular packages known assynaptic vesicles, released in a similar way to anyothervesicleduringexocytosis. Katz's work had immediate influence on the the basis of new post-war study fornerve agentsandpesticides, as he determined that the complex enzyme cycle waseasily disrupted.

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