Fat And Vitamin C – A Cancerous Combo

In the presence of fat, vitamin C may actually increase, rather than reduce, certain cancer causing chemicals, says a new study in the journal Gut. The findings were based on an analysis of the effects of fat and vitamin C on nitrite chemistry in the upper (proximal) stomach, which is especially vulnerable to pre-cancerous changes. Nitrites, which are present in certain preserved foodstuffs, may be converted to cancer causing compounds called nitrosamines.

Nitrosamines are formed in acidic conditions, such as those provided by stomach acid, but vitamin C inhibits their formation, by converting nitrite to nitric oxide. The researchers replicated the chemical conditions of the proximal stomach and measured the formation of nitrosamines, oxygen, and nitric oxide.

Without fat, they found that vitamin C curbed the levels of two nitrosamines by a factor of between 5 and 1,000. But when 10 percent fat was added, vitamin C actually boostedthe production of nitrosamines between 8- and 140-fold. The researchers say that nitric oxide, formed when vitamin C reacts with nitrite in acid, can diffuse into fat and then react with oxygen to form nitrosoamine generating chemicals.

Of concern to the researchers is the fact that fat remains in the proximal stomach for some time after a meal and also makes up a substantial amount of the cells lining the stomach. The authors believe the findings may be related to recent studies that showed vitamin C supplements fail to reduce overall cancer risk.

Related articles:
Vitamin C Overrated For Colds
Food, Notorious Food
Medicos Mull Advantageous Drug-Food Interactions

Source: BMJ Specialty Journals

, ,

Comments are closed.
1946 Photo Mary Kay Gum Grapefruit Vitamin C Lake Wales FL Crop Beautiful Rare
$19.99 1946 Photo Mary Kay Gum Grapefruit Vitamin C Lake Wales FL Crop Beautiful Rare picture
1980's Meijer Chewable Vitamin C Glass Bottle Plastic Stopper 6 3/4" Tall
$9.99 1980's Meijer Chewable Vitamin C Glass Bottle Plastic Stopper 6 3/4
1943 WW2 era beverage AD Florida Grapefruit Juice Art PT BOATS Vitamin C 011617
$7.86 1943 WW2 era beverage AD Florida Grapefruit Juice Art PT BOATS Vitamin C  011617 picture
Vitamin C, Natalie Imbruglia, & Mya magazine clippings
$1.35 Vitamin C, Natalie Imbruglia, & Mya  magazine clippings  picture
Vintage USSR Russian Medicine "VITAMIN - C" Empty Tin Box 1970's
$19.99 Vintage USSR Russian Medicine

Powered by WordPress. Designed by WooThemes