Forget pills! Just kill the murderers and rapists at birth! -There's a 'rational soultion' for ya!
Then, anyone who commits a crime in-spite of this (eg. kills someone) is merely a sane person who killed someone for a sane reason. Do what you wan't with them, punish them, help them. The normal ones are not my concern. It's the bloody phychopaths that are the real issue - JUST KILL THEM!!!