Yes, but the mutations occur in mitachondrial DNA located in the cytoplasm, not in the nucleus where "replicating " DNA is located and mix through recombination. Any mutations that may be facilitors of a crossover process must be with replicating DNA. Most of the mutations of mitachondrial DNA are a response to environmental input and effect changes such as weight loss or gain, which effects cell duplication in real time. These mutations are prolific but have nothing to do with replication. This is a clear distinction between duplication and replication and cannot be construed as an evolutionary process. More of this discussed elsewhere.