"What we observe is not nature itself, but nature exposed to our method of questioning."
-- Werner Heisenberg

http://www.notablebiographies.com/He-Ho/Heisenberg-Werner.html

http://nobelprize.org/nobel_prizes/physics/laureates/1932/heisenberg-bio.html

He wrote a book called "Physics and Beyond" which is my favorite (auto-)biography of a scientist.