"Nobel Prize in Medicine" John Gurdon Signed Announcement From 1984 For Sale
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"Nobel Prize in Medicine" John Gurdon Signed Announcement From 1984:
$99.99
Up for sale the "Nobel Prize in Medicine" John Gurdon Hand Signed Announcement Dated 1984.
ES-6371
Sir John Bertrand Gurdon FRS FMedSci MAE (born 2 October 1933) is an English developmental biologist. He is best known for his pioneering research in nuclear transplantation and cloning. He was awarded the Lasker Award in 2009. In 2012, he and Shinya Yamanaka were awarded the Nobel Prize for Physiology or Medicine for the discovery that mature cells can be converted to stem cells. Gurdon attended Edgeborough and then Eton College, where he ranked last out of the 250 boys in his year group at biology, and was in the bottom set in every other science subject. A schoolmaster wrote a report stating "I believe he has ideas about becoming a scientist; on his present showing this is quite ridiculous.” Gurdon explains it is the only document he ever framed; Gurdon also told a reporter "When you have problems like an experiment doesn't work, which often happens, it's nice to remind yourself that perhaps after all you are not so good at this job and the schoolmaster may have been right." Gurdon went to Christ Church, Oxford, to study classics but switched to zoology. For his DPhil degree he studied nuclear transplantation in a frog species of the genus Xenopus] with Michael Fischberg at Oxford. Following postdoctoral work at Caltech, he returned to England and his early posts were at the Department of Zoology of the University of Oxford (1962–71). Gurdon has spent much of his research career at the University of Cambridge, first at the MRC Laboratory of Molecular Biology (1971–83) and then at the Department of Zoology (1983–present). In 1989, he was a founding member of the Wellcome/CRC Institute for Cell Biology and Cancer (later Wellcome/CR UK) in Cambridge, and was its Chair until 2001. He was a member of the Nuffield Council on Bioethics 1991–1995, and Master of Magdalene College, Cambridge, from 1995 to 2002. In 1958, Gurdon, then at the University of Oxford, successfully cloned a frog using intact nuclei from the somatic cells of a Xenopus tadpole.This work was an important extension of work of Briggs and King in 1952 on transplanting nuclei from embryonic blastula cells and the successful induction of polyploidy in the stickleback, Gasterosteus aculatus, in 1956 by Har Swarup reported in Nature. At that time he could not conclusively show that the transplanted nuclei derived from a fully differentiated cell. This was finally shown in 1975 by a group working at the Basel Institute for Immunology in Switzerland. They transplanted a nucleus from an antibody-producing lymphocyte (proof that it was fully differentiated) into an enucleated egg and obtained living tadpoles. Gurdon's experiments captured the attention of the scientific community and the tools and techniques he developed for nuclear transfer are still used today. The term clone (from the ancient Greek word κλών (klōn, "twig")) had already been in use since the beginning of the 20th century in reference to plants. In 1963 the British biologist J. B. S. Haldane, in describing Gurdon's results, became one of the first to use the word "clone" in reference to animals. Gurdon and colleagues also pioneered the use of Xenopus (genus of highly aquatic frog) eggs and oocytes to translate microinjected messenger RNA molecules, a technique which has been widely used to identify the proteins encoded and to study their function.
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