New drug leaves diseased cells nowhere to hide

Posted by
DA Morgan on Apr 22, 2002 at 14:17

A revolutionary new breed of drugs will leave diseased and cancerous cells with nowhere to hide. The new drugs - which will only destroy diseased cells - are being touted as the biggest breakthrough since the late CÚsar Milstein discovered monoclonal antibodies in the 1980s.

Monoclonal antibodies can seek out and destroy diseased cells. It has taken two decades for these designer antibodies to make the grade as "magic bullet" drugs, but 10 are now on sale to treat diseases including breast cancer, leukaemia and arthritis.

The new drugs, called monoclonal T-cell receptors or mTCRs, could do even better because they can detect and destroy all diseased or cancerous cells, not just the 10 to 15 per cent targeted by monoclonal antibodies.

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