Gene Therapy by Mauro Giacca (2010, Hardcover)

Springer Milan

8847016428

9788847016422

92532113

Mauro Giacca

Gene Therapy

Hardcover

English

2010

Textbook

Xxi, 303 Pages

9.3in

6.1in

27.9 Oz

1 Vol.

Rb155-155.8

Abbreviations.- 1 Introduction to Gene Therapy .- 1.1 Genes as Drugs .- 1.2 Gene Therapy: An Overview .- Further Reading .- 2 Therapeutic Nucleic Acids .- 2.1 Protein-Coding Genes .- 2.2 Non-Coding Nucleic Acids.- Further Reading .- Selected Bibliography.- 3 Methods for Gene Delivery.- 3.1 Cellular Barriers to Gene Delivery.- 3.2 Direct Inoculation of DNAs and RNAs.- 3.3 Physical Methods.- 3.4 Chemical Methods.- 3.5 Viral Vectors.- Further Reading.- Selected Bibliography.- 4 Clinical Applications of Gene Therapy .- 4.1 Clinical Applications of Gene Therapy: General Considerations.- 4.2 Gene Therapy of Hematopoietic Stem Cells.- 4.3 Gene Therapy of Cystic Fibrosis.- 4.4 Gene Therapy of Muscular Dystrophies.- 4.5 Gene Therapy of Hemophilia.- 4.6 Gene Therapy of Cancer.- 4.7 Gene Therapy of Neurodegenerative Disorders.- 4.8 Gene Therapy of Eye Diseases.- 4.9 Gene Therapy of Cardiovascular Disorders.- 4.10 Gene Therapy of HIV Infection.- 4.11 Gene Therapy of Liver Diseases.- Further Reading.- Selected Bibliography.- 5 Ethical and Social Problems of Gene Therapy.- 5.1 Safety of Clinical Experimentation.- 5.2 Gene Therapy of Germ Cells.- 5.3 In Utero Gene Therapy.- 5.4 Gene Therapy of the Embryo.- 5.5 Gene Transfer for Cosmetic Appearance and Gene Doping.- Further Reading.- Selected Bibliography.- Subject Index.

2010

Scholarly & Professional

Clinical Medicine, Life Sciences / Molecular Biology, Internal Medicine, Genetics

Yes

Science, Medical