The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, gemic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigeme, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!
Product Identifiers
Publisher
Springer
ISBN-10
9400796765
ISBN-13
9789400796768
eBay Product ID (ePID)
195043714
Product Key Features
Format
Paperback
Language
English
Subject
Medicine: General
Dimensions
Weight
700g
Height
235mm
Width
155mm
Additional Product Features
Place of Publication
Dordrecht
Spine
25mm
Edited by
Karin B. Michels
Content Note
Biography
Date of Publication
22/02/2014
Genre
Medicine: General
Country of Publication
Netherlands
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