Gut flora link to Parkinson’s disease

Medical researchers in Finland hope that their discovery of a significant variation in the gut microbiota of Parkinson’s sufferers could be used to improve diagnostics for the disease and perhaps even prevent it. The new research was made possible by funding from the Michael J. Fox Foundation for Parkinson’s Research and the Finnish Parkinson Foundation.

The work, by researchers from the University of Helsinki and the Helsinki University Central Hospital (HUCH), adds to other recent studies that have linked gut flora to a range of conditions and diseases such as obesity, depression, schizophrenia, and Chlamydia.

In the new work, the researchers show that Parkinson’s disease sufferers have a significantly different microbiota in their intestines than their healthy counterparts. The findings are based on 72 subjects with Parkinson’s and an equal number of healthy controls.

“Our most important observation was that patients with Parkinson’s have much less bacteria from the Prevotellaceae family; unlike the control group, practically no one in the patient group had a large quantity of bacteria from this family,” explained HUCH neurologist Filip Scheperjans.

The researchers have not yet determined what the lack of Prevotellaceae bacteria in Parkinson’s sufferers means – do these bacteria perhaps have a property which protects their host from the disease? Or does this discovery merely indicate that intestinal dysfunction is part of the pathology of Parkinson’s? “It’s an interesting question which we are trying to answer,” Sheperjans says.

Interestingly, the researchers also discovered that the amount of bacteria from theEnterobacteriaceae family in the intestine was connected to the degree of severity of balance and walking problems in the patients. The more Enterobacteriaceae they had, the more severe the symptoms.

“We are currently re-examining these same subjects to determine whether the differences are permanent and whether intestinal bacteria are associated with the progression of the disease and therefore its prognosis,” explains Sheperjans.

“In addition,” he added, “we will have to see if these changes in the bacterial ecosystem are apparent before the onset of motor symptoms. We will of course also try to establish the basis of this connection between intestinal microbiota and Parkinson’s disease – what kind of mechanism binds them.”

Related:
Discuss this article in our forum
Diet shown to trigger mental illness
Evidence that probiotics alter brain function
Liver, not brain, may originate Alzheimer’s
Synthetic poo touted as solution to gastric woes

Source: University of Helsinki

, , ,

Comments are closed.

Kingsgate The Art of Keith Parkinson Art Fantastix Select Nr 8 #8 German Deutsch picture

Kingsgate The Art of Keith Parkinson Art Fantastix Select Nr 8 #8 German Deutsch

$81.00



CP ILLUSTREE SIGNED PARKINSON HOLLAND CHILDREN RACKET FLYING WHEELS - 54688 picture

CP ILLUSTREE SIGNED PARKINSON HOLLAND CHILDREN RACKET FLYING WHEELS - 54688

$2.60



Kingsgate: The Art Of Keith Parkinson picture

Kingsgate: The Art Of Keith Parkinson

$28.59



Complete Game of Thrones Dual Autograph Card Iwan Rheon and Art Parkinson picture

Complete Game of Thrones Dual Autograph Card Iwan Rheon and Art Parkinson

$39.75



1995 Playboy Chromium Covers Dian Parkinson #89 Graded FCGS 10 GEM MINT picture

1995 Playboy Chromium Covers Dian Parkinson #89 Graded FCGS 10 GEM MINT

$19.99



1995 Playboy Centerfold Collector Cards May Edition PICK FROM LIST UpTo 25%OFF picture

1995 Playboy Centerfold Collector Cards May Edition PICK FROM LIST UpTo 25%OFF

$0.99



1994 FPG Keith Parkinson The Fall Gate #23 0b6 picture

1994 FPG Keith Parkinson The Fall Gate #23 0b6

$2.83



KEITH PARKINSON 1994 FPG COMPLETE BASE CARD SET OF 90 FA FANTASY ART picture

KEITH PARKINSON 1994 FPG COMPLETE BASE CARD SET OF 90 FA FANTASY ART

$10.00



Glass Magic lantern slide GROUP OF EDWARDIAN MUSICIANS C1910 VIOLINS PARKINSONS picture

Glass Magic lantern slide GROUP OF EDWARDIAN MUSICIANS C1910 VIOLINS PARKINSONS

$18.06



Okmulgee OK, Parkinson Hotel, Automobiles, Oklahoma Vintage Postcard picture

Okmulgee OK, Parkinson Hotel, Automobiles, Oklahoma Vintage Postcard

$7.48



Powered by WordPress. Designed by WooThemes