Novel psychiatric drugs aimed at gut bacteria

Communication between the bacteria in our gut and our brain plays an important role in the development of psychiatric illness, say McMaster University researchers who are investigating how new psychiatric drugs might directly target intestinal flora.

McMaster neuroscientist Jane Foster contends that this brain-bacteria “cross-talk” plays an important role in the development of psychiatric illness, intestinal diseases and probably other health problems such as obesity. Foster’s work adds to a growing body of research linking inflammation and immune system dysfunction to mental illness.

Her research, published in Neurogastroenterology and Motility, shows that gut bacteria influences how the brain is wired for learning and memory. Radical new drugs could take advantage of this connection, she believes. “The wave of the future is full of opportunity as we think about how microbiota or bacteria influence the brain and how the bi-directional communication of the body and the brain influence metabolic disorders, such as obesity and diabetes.”

Foster’s study showed that the genes linked to learning and memory are altered in germ-free mice and, in particular, they are altered in the hippocampus. “The take-home message is that gut bacteria influences anxiety-like behavior through alterations in the way the brain is wired,” she summarized.

“We have a hypothesis in my lab that the state of your immune system and your gut bacteria – which are in constant communication – influences your personality,” Foster said. “The idea behind this research is to see if it’s possible to develop new therapies which could target the body, free of complications related to getting into the brain. We need novel targets that take a different approach than what is currently on the market for psychiatric illness.”

Related:
Hygiene Hypothesis linked to depression
Diet shown to trigger mental illness
Scientists manipulate immune system to produce “anti-Prozac”
Liver, not brain, may originate Alzheimer’s

Source: McMaster University

, ,

Comments are closed.

Damascus Steel Skinner Gut Hook Knife, Handmade Hunting Knife + Leather Sheath picture

Damascus Steel Skinner Gut Hook Knife, Handmade Hunting Knife + Leather Sheath

$39.50



6

6"HAND FORGED DAMASCUS STEEL HUNTING GUT HOOK KNIFE & RISEN HANDLE +sheath 2083

$26.99



3 Pcs Hunting Knife Sets Full Tang Bowie Survival Knife Gut Hook with Sheath picture

3 Pcs Hunting Knife Sets Full Tang Bowie Survival Knife Gut Hook with Sheath

$29.99



6

6"HAND FORGED DAMASCUS STEEL HUNTING GUT HOOK KNIFE & HORN HANDLE+SHEATH AH-2268

$26.99



Browning Primal Gut Tool Knife 3.13

Browning Primal Gut Tool Knife 3.13" 8Cr13MoV Steel Blade Black Polymer Handle

$20.99



8

8" Zomb-War Gut Hook Hunting Knife with Sheath Orange

$8.99



HANDMADE Full Tang HORN HANDLE Hunting SKINNER Knife Gut Hook + LEATHER Sheath picture

HANDMADE Full Tang HORN HANDLE Hunting SKINNER Knife Gut Hook + LEATHER Sheath

$14.94



Hafting Tomahawk Knife Makers Gut Hafting picture

Hafting Tomahawk Knife Makers Gut Hafting

$10.95



HANDMADE DAMASCUS HUNTING SKINNING KNIFE DEER STAG HORN ANTLER HANDLE GUT HOOK picture

HANDMADE DAMASCUS HUNTING SKINNING KNIFE DEER STAG HORN ANTLER HANDLE GUT HOOK

$39.99



MOSSY OAK Fixed Blade Hunting Knife 2PC Full Tang Straight Edge Gut Hook Blades picture

MOSSY OAK Fixed Blade Hunting Knife 2PC Full Tang Straight Edge Gut Hook Blades

$21.99



Powered by WordPress. Designed by WooThemes