Re: Help me escape VIII
Posted by fgjfjg on Aug 11, 2003 at 16:24
(129.59.237.136)Re: Help me escape VIII (Duncecap)
There is no evidence in the single b heme-containing complex II or E. coli QFR that the enzymes can act as proton pumps. It has been suggested that this is because the reactions catalyzed are not sufficiently exergonic to promote proton translocation. Nevertheless, in the single-subunit diheme containing B. subtilis SQR the uphill electron transfer reaction from menaquinol to succinate has shown to be sensitive to uncouplers, and this process is thought to be driven by the DmH, produced by the aerobic respiratory chain as discussed by Ohnishi and coworkers. It is also possible that the W. succinogenes QFR may produce DmH, which may occur by a Mitchellian type Q loop.