Has anyone made prednisolone in methyl cellulose? - 02/04/16 01:57 PM
Hi all,
If anyone has had experience with preparing and dosing prednisolone, I would greatly appreciate your advice on a few things.
I am looking to prepare prednisolone in 0.5% methyl cellulose - preferably at a concentration of 2 mg/mL to be dosed p.o. in mice.
Does anyone have experience using 0.5% MC as a vehicle for prednisolone? How is prednisolone’s stability in MC? Similarly, how often did you prepare it?
Any information would be great! Thanks!
If anyone has had experience with preparing and dosing prednisolone, I would greatly appreciate your advice on a few things.
I am looking to prepare prednisolone in 0.5% methyl cellulose - preferably at a concentration of 2 mg/mL to be dosed p.o. in mice.
Does anyone have experience using 0.5% MC as a vehicle for prednisolone? How is prednisolone’s stability in MC? Similarly, how often did you prepare it?
Any information would be great! Thanks!