Originally posted by trilobyte:
The mutation rates for parts of the human genome ARE known,
reference please...or retract. statement
Are you serious, trilobyte? Don't you know how to use Google? http://www.newsrx.com/newsletters/Gene-Therapy-Weekly/1996-04-29/0429961260323128GW.html http://jmg.bmjjournals.com/cgi/content/full/39/7/e40 http://www.bact.wisc.edu/Bact370/mutasummary.html
"Hot spots for point mutations can arise at sites preferred by mutagens, sites where replication/ repair enzymes frequently make errors, or sites that are poorly repaired by repair systems. As described below, large direct repeats can serve as hot spots for duplications and deletions, and certain insertion elements have site-specificity, so hot spots are not restricted to any particular type of mutation. The effect on your analysis will depend on just how frequently mutations occur at these sites, and whether or not they cause a phenotype that you are looking for."
"...however it is important to note that there are certain "hot spots" or "cold spots" for spontaneous mutations. (A "hot spot" is a site that has a higher rate of mutations than predicted from a normal distribution, and a "cold spot" is a site with a lower rate of mutations than predicted from a normal distribution.)"
Now stop with the infantile crap about retracting statements. Learn some biology
and stop debating topics about which you know nothing.