Women as a group are more susceptible to getting autoimmune diseases than men. There is definitely some genetic risk factor(s), as Lupus often have a higher than normal occurrence in their families of things like Lupus, Fibromyalgia, Chronic fatigue Syndrome, Rheumatoid Arthritis and other auto-immune diseases. I myself have Chronic FAtigue Syndrome, and I have a cousin who has it, another who has Lupus, and an aunt with severe RA, within two generations from me, that I know of. That's much higher than statistical probability would project.

Lupus has two forms, depending on whether the epidermis or the internal organs are most highly involved. Lupus erythematosus means "red wolf" and is so called because of the reddish rash on the face and the butterfly pattern of reddish discoloration that crosses the bridge of the nose and the cheeks, causing a somewhat "wolfish" appearance. It is exacerbated by sunlight and UV radiation.